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Other links at Articles > Pathology and Lab Medicine |
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Growth Factor Gene Therapy Delivered Locally to Periodontal Bone Lesions
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Experiments in rats show that human platelet-derived growth factor-B (PDGF-B) can be safely delivered by adenovirus in a collagen matrix to tooth-supporting alveolar bone defects, according to a report scheduled for publication in the May issue of Human Gene Therapy. Reuters Health Information
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Statins May Impair Muscle Cell Repair and Regeneration
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With their antiproliferative effects, high doses of statins reduce the ability of muscle progenitor cells (i.e., satellite cells) to repair and regenerate, according to research reported at the American Physiological Society conference - The Integrative Biology of Exercise V, which wrapped up Saturday in Hilton Head, South Carolina. Reuters Health Information
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Breast Cancer Risk Elevated in Male BRCA 1 and 2 Mutation Carriers
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Previous studies have shown that men who carry germline mutations in the BRCA2 gene are at greater risk of developing breast cancer than men in the general population. New research suggests that the same is true for men who carry germline mutations in the BRCA1 gene. Reuters Health Information
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Cells Engineered to Reduce Arterial Plaque
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Descendants of hematopoietic progenitor cells that were genetically engineered to express apolipoprotein AI (apoAI) counter the accumulation of cholesterol on artery walls, according to a study in mice by researchers from Vanderbilt University reported in the August issue of Arteriosclerosis, Thrombosis, and Vascular Biology. ApoAI is the major protein component of high-density lipoprotein. Reuters Health Information
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