Four out of five children with juvenile idiopathic arthritis had a good clinical response to abatacept during a long-term open-label extension trial. The safety profile was good, and the level of response often increased as treatment went on, the researchers report. Reuters Health Information
The risk of gout is high in patients with hypertension. Which classes of antihypertensive drugs augment that risk? Which classes of drugs reduce it? Medscape Cardiology
Dr. Cohen discusses disease remission and treatment for RA, with a focus on treatment options for patients who have failed anti-TNF therapy. Medscape Rheumatology
Taking into account infliximab serum levels when making dose-adjustments could lead to better disease control, new research hints. Nature Reviews Rheumatology
In contrast to other trials, a French study shows the anti-CD20 monoclonal antibody rituximab to be well tolerated and clinically effective in patients with systemic lupus erythematosus (SLE). Reuters Health Information
The purpose of this study was to determine muscle and tendon protein fractional synthesis rates at rest, and after kicking exercises, in patients with knee osteoarthritis receiving NSAIDs. Medicine and Science in Sports and ExerciseŽ