A systematic review shows that hepatoxicity after therapeutic dosing of acetaminophen in children is rarely reported in defined-population studies. Medscape Medical News
Inherited genetic variations are associated with early response, relapse, and/or pharmacokinetics of chemotherapy in children with acute lymphoblastic leukemia. Medscape Medical News
A 93-gene signature associated with the presence of EGFR mutations may be a favorable prognostic marker in patients with early-stage nonsmall-cell lung cancer. Medscape Medical News
A review highlights key concerns and research gaps among studies of nonpharmaceutical interventions, such as hand washing and mouth covering. Medscape Medical News
In HIV-infected patients, the anti-TB medication rifampin use limits the effective concentrations of nevirapine more than efavirenz, suggesting that efavirenz is a better choice of non-nucleoside reverse-transcriptase inhibitor in such patients. Reuters Health Information