The authors report on a case of a woman with marked insulin resistance in whom the use of U-500 insulin in continuous subcutaneous insulin infusion resulted in a marked improvement. The British Journal of Diabetes and Vascular Disease
The discovery of the role of PKC-beta, the pathogenesis of end-stage renal disease, could unlock new therapies for this serious complication of diabetes. Medscape Nephrology
SGLT2 inhibitors have significant potential in the treatment of type 2 diabetes as a class of drugs that can effectively lower blood glucose while avoiding weight gain, hypoglycemia, and edema. Medscape Diabetes & Endocrinology
In a randomized, double-blind, placebo-controlled study, an oral contraceptive combination decreased prolonged, frequent, or heavy menstrual bleeding and improved iron metabolism vs placebo. Medscape Medical News
Might erythropoietin have neuroprotective effects in the growing population of premature infants with neurodevelopmental disabilities? Nature Reviews Neurology
In children with type 1 diabetes, mixing insulin aspart and detemir in the same syringe has the same effect on blood sugar levels as giving the injections separately, investigators report in the May 26th online issue of Diabetes Care. Reuters Health Information