Imatinib is being tested in a clinical trial after compassionate use in a critically ill child with plexiform neurofibroma showed a dramatic response. Medscape Medical News
Delivery of drugs to malignant brain tumors is challenging. CED can overcome some of the difficulties so pharmacological agents that would not normally cross the BBB can be used for treatment. Expert Review of Neurotherapeutics
Questions and answers for this paroxysmal nocturnal hemoglobinuria symposium: clinicians will better understand how to make a diagnosis, comprehend what is happening in patients, and advise treatment.
Tumor-associated macrophages, which play a key role in the pathogenesis of high-grade breast cancers, could serve as prognostic markers and potential therapeutic targets. Expert Review of Molecular Diagnostics